Using a computationally efficient method, the package can be used to find the corrected coverage estimate of a credible set of putative causal variants from Bayesian genetic fine-mapping. The package can also be used to obtain a corrected credible set if required; that is, the smallest set of variants required such that the corrected coverage estimate of the resultant credible set is within some user defined accuracy of the desired coverage. Maller et al. (2012) <doi:10.1038/ng.2435>, Wakefield (2009) <doi:10.1002/gepi.20359>, Fortune and Wallace (2018) <doi:10.1093/bioinformatics/bty898>.
| Version: | 1.2.1 |
| Depends: | R (≥ 3.5.0) |
| Imports: | data.table, magrittr, stats, matrixStats, Rcpp |
| LinkingTo: | Rcpp, RcppArmadillo |
| Suggests: | covr, dplyr, knitr, mvtnorm, rmarkdown, testthat, pkgdown |
| OS_type: | unix |
| Published: | 2019-12-06 |
| DOI: | 10.32614/CRAN.package.corrcoverage |
| Author: | Anna Hutchinson [aut, cre], Chris Wallace [aut], Kevin Kunzmann [ctb] |
| Maintainer: | Anna Hutchinson <anna.hutchinson at mrc-bsu.cam.ac.uk> |
| BugReports: | https://github.com/annahutch/corrcoverage/issues |
| License: | MIT + file LICENSE |
| URL: | https://annahutch.github.io/corrcoverage |
| NeedsCompilation: | yes |
| SystemRequirements: | C++11 |
| Materials: | README NEWS |
| CRAN checks: | corrcoverage results |
| Reference manual: | corrcoverage.pdf |
| Vignettes: |
Corrected Credible Set Useful Info From GWAS Summary Statistics to Credible Sets Correcting the Coverage of Credible Sets |
| Package source: | corrcoverage_1.2.1.tar.gz |
| Windows binaries: | r-devel: not available, r-release: not available, r-oldrel: not available |
| macOS binaries: | r-release (arm64): corrcoverage_1.2.1.tgz, r-oldrel (arm64): corrcoverage_1.2.1.tgz, r-release (x86_64): corrcoverage_1.2.1.tgz, r-oldrel (x86_64): corrcoverage_1.2.1.tgz |
| Old sources: | corrcoverage archive |
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