depower: Power Analysis for Differential Expression Studies

Provides a convenient framework to simulate, test, power, and visualize data for differential expression studies with lognormal or negative binomial outcomes. Supported designs are two-sample comparisons of independent or dependent outcomes. Power may be summarized in the context of controlling the per-family error rate or family-wise error rate. Negative binomial methods are described in Yu, Fernandez, and Brock (2017) <doi:10.1186/s12859-017-1648-2> and Yu, Fernandez, and Brock (2020) <doi:10.1186/s12859-020-3541-7>.

Version: 2025.1.20
Depends: R (≥ 4.2.0)
Imports: Rdpack, stats, mvnfast, glmmTMB, dplyr, multidplyr, ggplot2, scales
Suggests: tinytest, rmarkdown
Published: 2025-01-23
Author: Brett Klamer ORCID iD [aut, cre], Lianbo Yu ORCID iD [aut]
Maintainer: Brett Klamer <code at brettklamer.com>
License: MIT + file LICENSE
URL: https://brettklamer.com/work/depower/, https://bitbucket.org/bklamer/depower/
NeedsCompilation: no
Language: en-US
Citation: depower citation info
Materials: README NEWS
CRAN checks: depower results

Documentation:

Reference manual: depower.pdf

Downloads:

Package source: depower_2025.1.20.tar.gz
Windows binaries: r-devel: not available, r-release: not available, r-oldrel: not available
macOS binaries: r-release (arm64): not available, r-oldrel (arm64): not available, r-release (x86_64): depower_2025.1.20.tgz, r-oldrel (x86_64): not available
Old sources: depower archive

Linking:

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