Identifying latent genetic interactions in genome-wide association studies using the Latent Interaction Testing (LIT) framework. LIT is a flexible kernel-based approach that leverages information across multiple traits to detect latent genetic interactions without specifying or observing the interacting variable (e.g., environment). LIT accepts standard PLINK files as inputs to analyze large genome-wide association studies.
| Version: | 1.0.0 |
| Imports: | Rcpp (≥ 1.0.11), genio, CompQuadForm |
| LinkingTo: | Rcpp, RcppArmadillo, RcppEigen |
| Suggests: | testthat (≥ 3.0.0), knitr, rmarkdown |
| Published: | 2023-08-15 |
| DOI: | 10.32614/CRAN.package.lit |
| Author: | Andrew Bass [aut, cre], Michael Epstein [aut] |
| Maintainer: | Andrew Bass <ajbass at emory.edu> |
| License: | LGPL-2 | LGPL-2.1 | LGPL-3 [expanded from: LGPL] |
| URL: | https://github.com/ajbass/lit |
| NeedsCompilation: | yes |
| Materials: | README NEWS |
| CRAN checks: | lit results |
| Reference manual: | lit.pdf |
| Vignettes: |
LIT: Latent Interaction Testing |
| Package source: | lit_1.0.0.tar.gz |
| Windows binaries: | r-devel: lit_1.0.0.zip, r-release: lit_1.0.0.zip, r-oldrel: lit_1.0.0.zip |
| macOS binaries: | r-release (arm64): lit_1.0.0.tgz, r-oldrel (arm64): lit_1.0.0.tgz, r-release (x86_64): lit_1.0.0.tgz, r-oldrel (x86_64): lit_1.0.0.tgz |
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