Individual Dose Optimization using Population Pharmacokinetics


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Documentation for package ‘posologyr’ version 1.2.7

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poso_dose_auc Estimate the dose needed to reach a target area under the concentration-time curve (AUC)
poso_dose_conc Estimate the optimal dose to achieve a target concentration at any given time
poso_estim_map Estimate the Maximum A Posteriori individual parameters
poso_estim_mcmc Estimate the posterior distribution of individual parameters by MCMC
poso_estim_sir Estimate the posterior distribution of individual parameters by SIR
poso_inter_cmin Estimate the optimal dosing interval to consistently achieve a target trough concentration (Cmin)
poso_replace_et Update a model with events from a new rxode2 event table
poso_simu_pop Estimate the prior distribution of population parameters
poso_time_cmin Estimate the time required to reach a target trough concentration (Cmin)