Placental Epigenetic Clock to Estimate Aging by DNA Methylation


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Documentation for package ‘rplec’ version 0.1.3

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aging Residual DNA-methylation-based (DNAm) gestational age
beta_v_indices Indices for random beta values
bmiq_norm_450k Normalize DNA methylation values
download_beta_values_case Access Beta values at individual CpG sites for case group
download_beta_values_control Access Beta values at individual CpG sites for control group
ga Gestational age for both case and control groups
ipla Identify placental aging
phenotype Phenotype for both case and control groups
plec Estimate DNA-methylation-based gestational age
plec_int_coef Intercept and coefficients of placental epigenetic clock
plec_scaler_mean Mean values of the scalers of placental epigenetic clock
plec_scaler_scale Scale values of the scalers of placental epigenetic clock
probe_info_450k Probe info for 450K
qc Perform quality control