colocPropTest: Proportional Testing for Colocalisation Analysis
Colocalisation analysis tests whether two traits share a causal genetic variant in a specified genomic region. Proportional testing for colocalisation has been previously proposed [Wallace (2013) <doi:10.1002/gepi.21765>], but is reimplemented here to overcome barriers to its adoption. Its use is complementary to the fine- mapping based colocalisation method in the 'coloc' package, and may be used in particular to identify false "H3" conclusions in 'coloc'.
| Version: | 0.9.1 |
| Depends: | magrittr, data.table |
| Imports: | car, coloc, graphics, stats, utils |
| Suggests: | knitr, plotrix, testthat (≥ 3.0.0) |
| Published: | 2024-06-11 |
| DOI: | 10.32614/CRAN.package.colocPropTest |
| Author: | Chris Wallace 
[aut, cre] |
| Maintainer: | Chris Wallace <chris.x.wallace at gsk.com> |
| License: | GPL (≥ 3) |
| NeedsCompilation: | no |
| Materials: | README |
| CRAN checks: | colocPropTest results |
Documentation:
| Reference manual: | colocPropTest.pdf |
| Vignettes: |
Proportional colocalisation |
Downloads:
| Package source: | colocPropTest_0.9.1.tar.gz |
| Windows binaries: | r-devel: colocPropTest_0.9.1.zip, r-release: colocPropTest_0.9.1.zip, r-oldrel: colocPropTest_0.9.1.zip |
| macOS binaries: | r-release (arm64): colocPropTest_0.9.1.tgz, r-oldrel (arm64): colocPropTest_0.9.1.tgz, r-release (x86_64): colocPropTest_0.9.1.tgz, r-oldrel (x86_64): colocPropTest_0.9.1.tgz |
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